منابع مشابه
A gut feeling about plasmablasts.
6 conserved aspartate residues (designated " D " in amino acid notation) in the molecule (see figure) are permissive to change, but the other 2 (D109 and D156) are critical for function with resulting marked impairment or total loss of function when mutated. Why aspartate? This amino acid is more highly conserved than others because of several attributes that include a short side chain, a high ...
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The gut microbiota of patients recently diagnosed with rheumatoid arthritis is enriched in microbes belonging to the Prevotella genus.
متن کاملBeing human is a gut feeling
Some metagenomic studies have suggested that less than 10% of the cells that comprise our bodies are Homo sapiens cells. The remaining 90% are bacterial cells. The description of this so-called human microbiome is of great interest and importance for several reasons. For one, it helps us redefine what a biological individual is. We suggest that a human individual is now best described as a supe...
متن کاملMicrobiota and Neurological Disorders: A Gut Feeling
In the past century, noncommunicable diseases have surpassed infectious diseases as the principal cause of sickness and death, worldwide. Trillions of commensal microbes live in and on our body, and constitute the human microbiome. The vast majority of these microorganisms are maternally derived and live in the gut, where they perform functions essential to our health and survival, including: d...
متن کاملA gut feeling about multiple sclerosis.
Multiple sclerosis (MS) is an autoimmune inflammatory disease of the central nervous system (CNS) that constitutes the leading cause of neurologic disability in young adults (1). Th1 and Th17 effector T cells (Teffs) are thought to play a central role in the pathogenesis of MS (2, 3). Thus, the study of the mechanisms that control Teffs and the regulatory T cells (Tregs) that suppress them is l...
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ژورنال
عنوان ژورنال: Trends in Endocrinology & Metabolism
سال: 2013
ISSN: 1043-2760
DOI: 10.1016/j.tem.2013.03.001